MRI/DTI

The Innovation

Despite over 25 years of research, traditional pharmaceutical therapy has failed to address the short and long-term effects of traumatic injury. At Equinox, our proprietary “Neuro-Infuse” therapy was designed around the premise that the injury itself is multimodal in nature. Treating TBI means treating each component that contributes to long term cognitive decline: oxidative stress, edema, excitotoxicity and cell death. This multimodal therapy is specifically constructed to target the secondary injury cascade rather than focusing on one single element. Our formula includes mixtures of FDA approved vitamins, glutathione, amino acids and co-factor is safe, non-toxic and has an increasing body of literature supporting their use, at supra-physiologic levels, in the treatment of traumatic brain injury.

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The Science

While numerous attempts have been made to harness neuroprotective approaches in the treatment of traumatic brain injury and “concussion”, virtually no therapeutic interventions have successfully been created. Traumatic brain injury simply relies on physical and cognitive rest with very little actual intervention against the cellular cascade responsible for the pathophysiology of “brain trauma.” No single drug has proven effective and, as such, the concept of a multimodal, neuro-prophylactic compounds or supplement holds great promise.

The value of this theory is especially relevant as we expand our knowledge regarding the relationship between numerous sub-concussive blows and/or repetitive concussive impacts and the development of some form of chronic neurodegenerative disease. As the use of nutraceuticals has expanded and the encouraging results from various laboratory studies demonstrating the multi-mechanistic neuroprotective properties of many of these naturally occurring compounds, so has their potential to treat and manage traumatic brain injury.

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TBI care in your clinic

Each easy to administer IV (intravenous) infusion, lasts 30 to 40-minutes and can be given at your office or in the comfort of your patient’s home. Every infusion contains a powerful mixture of vitamins, minerals, alkalinizing fluids and cofactors (i.e. glutathione), designed to reduce your patient’s oxidative stress, improve their overall nutritional status, improve cognitive function, increase their energy and improve the quality of their day to day lives.

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The Incidence  And The Cost (formally a new pathway)

In 2015 the CDC estimated that 2.8 million new TBI cases would occur within the United States. This incidence includes 2.5 million TBI-related emergency department visits, 288,000 TBI-related hospitalizations, and 57,000 TBI-related deaths. An estimated 10 million people will be affected annually by TBI, and by the year 2020, it will surpass many diseases as the major cause of death and disability.

Additionally, data (Zaloshnja, Miller, Langlois, & Selassie, 2008) suggest that the TBI-related disability after hospitalization to be 3.2 million with approximately 775,000 older adults living with long-term disability associated with TBI (Zaloshnja et al., 2008). Northwestern estimates that a patient may incur a lifetime costs of treatment that ranges from $85,000 to $3 million and that unemployment rate two years after diagnosis with TBI can reach 60 percent, compared to the national unemployment average of 5.1 percent.

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Measurable Patient Improvement

In conjunction with Equinox’s unique proprietary (patented?) scanning methodology patients can be evaluated before treatment begins or before they are even subjected to any type of traumatic brain injury. Patients can then be treated for 4-6 months and then rescanned in an effort to evaluate their ongoing therapeutic

regimen. In addition, patients can be evaluated with cognitive and emotional testing to empirically determine their levels of improvement. improved cognitive function, memory, dexterity, and mood, along with radiologic data, which all important criteria for evaluation. This paradigm allows for a more complex evaluation of your patient’s well-being and functional status while reducing the biochemical cascade caused by multiple traumas. This unique approach will help offset the long-term consequences of head injury.